Maja Zečević, Zoran Marjanović, Goran Janković, Danijela Djerić, Zorica Jovanović, Vesna Marjanović, Jelena Lilić, Danijel Mančić, Dragana Lazarević

DOI Number
First page
Last page


The pandemic caused by the SARS-CoV-2 virus had a significant impact on providing health services the world over and is reflected in pediatric surgery also. The aim of this study was to determine the differences in the prevalence of forms of appendicitis among children during and prior to the pandemic, and to compare the demographic characteristics. A retrospective study which covered a period from September 1, 2018 until September 1, 2021 and all the patients who underwent surgery for acute appendicitis was carried out. Demographic and clinical data were collected and analysed. The study included a total of 267 patients. Prior to the pandemic a total of 160 children underwent surgical treatment, 61.9% boys and 38.1% girls, while during the pandemic a total of 107 underwent surgical treatment, mostly boys 68,2%, and to a lesser extent, girls 31.8%. The average age of the patients was 11.0±3.9 years. Even though there is a difference in the number of children who underwent surgical treatment for perforated appendicitis prior to and during the Covid-19 pandemic, 54:44 or 33.8:41.1%, the difference is not statistically significant. During the pandemic, two patients who tested positive for the SARS-CoV-2 virus received surgical treatment for a perforated appendicitis. The Covid-19 pandemic had an impact on the healthcare system worldwide. In most centers for pediatric surgery, there was an increased incidence of perforated appendicitis without significant deviations in the demographic characteristics, which correlates with the results of this study


appendicitis, children, Covid-19 pandemic

Full Text:



Bong CL, Brasher C, Chikumba E, McDougall R, Mellin-Olsen J, Enright A The COVID-19 pandemic: efects on low and middle-income countries. Anesth Analg 2020; 131:8692.

Snapiri O, Rosenberg Danziger C, Krause I, et al. Delayed diagnosis of paediatric appendicitis during the COVID-19 pandemic. Acta Paediatr 2020; 109(8):1672–1676.

La Pergola E, Sgrò A, Rebosio F, et al. Appendicitis in Children in a Large Italian COVID-19 Pandemic Area. Front Pediatr 2020; 8:600320.

McCollough M, Sharieff GQ. Abdominal surgical emergencies in infants and young children. Emer Med Clinics North Am 2003; 21(4):909935.

Colvin D, Lawther S. A surge in appendicitis: Management of paediatric appendicitis during the COVID-19 surge in the Royal Belfast Hospital for Sick Children. Ulster Med J 2021; 90(2):86–89.

Kvasnovsky C, Shi Y, Rich BS, et al. Limiting hospital resources for acute appendicitis in children: Lessons learned from the U.S. epicenter of the COVID-19 pandemic. J Pediatr Surg 2021; 56(5):900904.

Esparaz JR, Chen MK, Beierle EA, et al. Perforated Appendicitis during a Pandemic: The Downstream Effect of COVID-19 in Children. J Surg Res 2021; 268:263–266.

Schäfer FM, Meyer J, Kellnar S, et al. Increased Incidence of Perforated Appendicitis in Children During COVID-19 Pandemic in a Bavarian Multi-Center Study. Front Pediatr 2021; 9:683607. doi:10.3389/fped.2021.683607

Lee-Archer P, Blackall S, Campbell H, Boyd D, Patel B, McBride C. Increased incidence of complicated appendicitis during the COVID-19 pandemic. J Paediatr Child Health 2020; 56(8):1313–1314.

Gerall CD, DeFazio JR, Kahan AM, et al. Delayed presentation and sub-optimal outcomes of pediatric patients with acute appendicitis during the COVID-19 pandemic. J Pediatr Surg 2021; 56(5):905-910. doi:10.1016/j.jpedsurg.2020.10.008

Pines JM, Zocchi MS, Black BS, et al. Characterizing pediatric emergency department visits during the COVID-19 pandemic. Am J Emerg Med 2021; 41:201–204.

Hassoun A, Kadenhe-Chiweshe A, Sharma M. New York's COVID-19 shelter-in-place and acute appendicitis inchildren. J Pediatr Surg 2021; 56:635–636.

Jackson RJ, Chavarria HD, Hacking SM. A Case of Multisystem Inflammatory Syndrome in Children Mimicking Acute Appendicitis in a COVID-19 Pandemic Area. Cureus 12(9): e10722. DOI 10.7759/cureus.10722

Anderson JE, Campbell JA, Durowoju L, et al. COVID-19-associated multisystem inflammatory syndrome in children (MIS-C) presenting as appendicitis with shock. J Pediatr Surg Case Rep 2021; 71:101913. doi:10.1016/j.epsc.2021.101913

Acevedo MJ, Steffey D, Dillon JE, Lee JT, Worhunsky DJ. Concurrent COVID-19 infection in children with acute appendicitis: A report of three cases. Radiol Case Rep 2021; 16:2972–2977



  • There are currently no refbacks.

© University of Niš, Serbia
Creative Commons licence CC BY-NC-ND
ISSN 0354-4699 (Print)
ISSN 2406-050X (Online)