Ranko M. Kutlešić, Jasmina Popović, Milan Stefanović, Predrag Vukomanović, Jelena Milošević Stevanović, Danka Mostić Stanišić

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Hyperprolactinaemia is one of the most frequent causes of anovulation, resulting in infertility and hypoestrogenic  state with consequences on overall women’s health. Recent investigations on biological actions of prolactin, especially prolactin of extrapituitary origin, expand our knowledge  on prolactin role in the human organism and open new questions connected with female reproductive function and treatment of female infertility. This article represents the review of current knowledge on prolactin physiology, etiopathogenesis, clinical features, assessment , differential diagnosis ,and teatment of hyperprolactinaemia in the female patient.


prolactin, hyperprolactinaemia, physiology, female infertility, treatment

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