SYNTHESIS AND SPECTROSCOPIC CHARACTERIZATION OF NEW SOLID SOLUTION CONTAINING Mg(II) AND Cu(II) COMPLEXES WITH HEXADENTATE 1,3-PROPANEDIAMINE-N,N,N’,N’-TETRAACETATE (1,3-PDTA) LIGAND: IN VITRO ANTIFUNGAL ACTIVITY OF 1,3-PDTA-Cu(II) COMPLEXES

Ivana M. Stanojević, Jelena Gitarić, Darko P. Ašanin, Biljana Đ. Glišić, Nenad S. Drašković, Sanja Živković, Tanja P. Vasić

DOI Number
https://doi.org/10.2298/FUPCT2001047S
First page
047
Last page
056

Abstract


New solid solution containing Mg(II) and Cu(II) complexes with hexadentate 1,3-propanediamine-N,N,N’,N’-tetraacetate ligand (1,3-pdta), [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O was synthesized and structurally characterized by elemental microanalyses, molar conductivity and spectroscopic (IR and UV-Vis) measurements. The spectroscopic data of [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O were compared with those for [Mg(H2O)6][Cu(1,3-pdta)].2H2O  complex of the known molecular structure determined by single-crystal X-ray diffraction analysis (Rychlewska et al., 2000). In vitro growth inhibition activity of [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O and [Mg(H2O)6][Cu(1,3-pdta)].2H2O against Colletotrichum acutatum and their effects on this fungus sporulation level are investigated. The obtained results showed that the highest percentage of inhibition for mycelium growth was achieved at a concentration of 500 µg/mL for the investigated complexes. The biological activities of the investigated complexes were compared with those for the commercial formulation of fungicide captan (Method 480 SC). 

Keywords

3-pdta-copper(II) complexes, IR spectra, electronic absorption spectra, antifungal activity, Colletotrichum acutatum

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